AMGTA Commissions First Research Project on Environmental Sustainability of Metal 3D Printing

In November, the non-commercial, global trade group AMGTA, or the Additive Manufacturer Green Trade Association, was launched in order to promote the many environmental, green benefits of using additive manufacturing (AM) rather than conventional technology. The AMGTA has just commissioned its first university research project, which will be a systematic review of the environmental sustainability of metal 3D printing. The review will be literature-based, and will look at existing studies focused on the environmental benefits of the technology.

Based in Hollywood, Florida, the non-profit AMGTA is unaffiliated, meaning it is open to any industry stakeholder or additive manufacturer who meets specific criteria that are related to sustainability in processes and production.

“The AMGTA seeks to educate the public and industry about these positive environmental benefits, promote the adoption of AM as an alternative to traditional manufacturing, develop best practices for additive manufacturing, and help the organization’s members grow their businesses and acquire new customers,” the website states. “In order to accomplish these goals, the AMGTA will engage in marketing and advertising campaigns, sponsor and conduct research and publish the results, and grow the organization’s membership.”

3D printing has many benefits in terms of sustainability. For instance, it uses less material, which equals less waste, and also uses less energy than other processes. Additionally, parts can also be fabricated closer to the consumer, so that helps lower the carbon footprint as well by reducing, or even negating, shipping travel.

According to Sherry Handel, the AMGTA’s Executive Director, the commissioned research paper will be “…describing where metal additive manufacturing provides environmental benefits compared to older manufacturing methods.”

“This research may also reveal areas in the manufacturing process where AM could cause higher environmental impacts than older manufacturing methods. Through rigorous, independent and ongoing research the AMGTA will publish research findings and share with industry and other key stakeholders what our eco-footprint is now and what we will need to focus on in the future to be more sustainable.”

The AMGTA announced that it has chosen Dr. Jeremy Faludi, PhD, LEED AP BD+C, a design strategist and sustainable engineering researcher, to oversee the project. With degrees from UC Berkeley, Stanford University, and Reed College, Dr. Faludi is currently an assistant professor of design engineering at the Technical University of Delft (TU Delft) in the Netherlands, focused on green 3D printing and design for the circular economy. He has previously taught at Stanford and the Minneapolis College of Art and Design, and is also an adjunct faculty member of engineering at Dartmouth College’s Thayer School of Engineering.

Dr. Jeremy Faludi, PhD, LEED AP BD+C

“We are excited to announce our first research project and thrilled to be able to work with Dr. Faludi. This project will provide our membership and the public in general with an excellent survey of existing research on the sustainability benefits of AM. Dr. Faludi is a renowned researcher within this field, and we are looking forward to understanding better the existing scope of research on this topic,” Handel said.

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(Images: Additive Manufacturer Green Trade Association)

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A General Review of Methods and Materials for 3D Food Printing

Researchers from the University of Birmingham published a paper that reviews various methods and materials related to the scope of food 3D printing, which they write is “an area of great promise to provide an indulgence or entertaining experience, personalized food product, or specific nutritional needs.”

“One of the more challenging and complex areas of AM are in the emerging field of gastronomy, or in other words, “3D Food printing” [4]. The ability to selectively deposit material within a 3D volume and, hence, gradate the composition offers the possibility of controlled production of complex structures for altering texture, taste, and morphology in food products,” they write. “Manipulation of microstructures by regulating the mixing and selective deposition of materials can allow regulation of fracture, breakdown, or dissolution mechanics during product use, which gives the possibility of a range of functional and novel foods.”

AM has many advantages, including increased efficiency, design freedom, reduced waste, and faster turnaround. The technology enables customization and personalization, and has seen promising use in several application areas, including healthcare, aerospace, construction, fashion, and gastronomy.

Haddock, 3D printed by Matís using the Foodini.

There have been several reviews in recent years on various aspects of 3D food printing, including 3D printable food formulations, methods applied to designing food materials, environmental implications and possible legal challenges, and advantages and disadvantages of various food 3D printers. But the field is growing, and “there is a need to collate and categorise published reports and to consolidate these developments.”

“As such, we can have a better understanding of the accomplishments to date, and potential areas for future studies,” the researchers state.

ASTM F2792-12a has categorized seven specific AM headings, though different acronyms are often used to describe the same process:

  1. Vat Polymerization
  2. Material Extrusion
  3. Directed Energy Deposition (DED)
  4. Powder Bed Fusion (PBF)
  5. Binder Jetting
  6. Material Jetting
  7. Sheet Lamination

Five of these so far – vat polymerization, extrusion, PBF, binder jetting, and inkjet printing – have been used to print food.

“The same process principles, for AM in general, also apply to 3D Food printing,” they write. “However, different degrees of pre-processing, such as fine-tuning of food recipes, and post-processing, such as cooking and oven drying, might be necessary for 3D food printing [4].”

(Image: Natural Machines)

There are some unique challenges involved with 3D food printing. For instance, some 3D printed food samples show a high microbial concentration when stored in air, which could mean that further consideration is needed for hygienic equipment design. Also, many consumers often negatively view foods that “appear to have undergone a lot of processing.” But the potential seems to far outweigh any issues.

First, reducing food waste and “increasing the usage of existing food materials” can help streamline the supply chain and resolve food shortages. One example is Upprinting Food, a company that uses food waste as the “ink” for food 3D printers by combining ingredients like fruits, bread, and vegetables to make a puree that can be 3D printed. The prints are then seasoned, baked, and dehydrated “so that the resulting product is nicely crunchy and long durable.”

(Image: Upprinting Foods)

Many food manufacturing processes, like baking and shaping, are eliminated through the use of 3D printing, which saves time, and the technology also makes food transport easier. 3D printed food can also be used to customize food in order to treat malnutrition, or help people with special dietary needs, like those with Celiac disease or dysphagia. It can promote low-carbon food products, such as insects, and 3D printing meatless meat reduces environmental impact.

Vegan 3D printed steak (Image: Novameat)

You can see a chronological summary of reported 3D printing methods and food materials, such as milk chocolate, wheat dough, Vegemite, powdered broccoli and carrots, and heat-induced egg yolk paste, that have been used in Table 1.

“For 3D food printing to become practical, precise calibration of printing parameters should be carried out, dictated by the mechanical properties of the material. Furthermore, the study of the relationship between the rheological characteristics and their connection with printing parameters is key for improving the overall quality of 3D printed food [2],” the researchers noted.

“In general, 3D printable materials must exhibit a controllable viscoelastic response, must form stable structures capable of withstanding compressive stresses from capillary forces, and must not shrink too much when undergoing drying, to avoid deformation and/or fissure formation [58]. These materials must be able to hold their shape once deposited. They need to be printable into defined shapes without slumping, spreading, or bridging.”

It’s important to classify the materials into examples that are “natively printable,” like hydrogels and dairy, and “non-natively printable,” such as meat and plants. But this will be difficult, as multiple factors affect printability, there isn’t a consensus on how to predict or assess shape fidelity, and just because one material is 3D printable with one AM method doesn’t mean that it’s the case for another.

3D printed sweets. (Image: 3D Systems)

The most suitable 3D food printing materials are carbohydrates, fats, fiber, functional components, and proteins, along with hydrogels like alginate and gelatin, and extrusion is the most widely adopted AM technique for 3D food printing. A material needs to display shear thinning behavior for this, which means that it can be extruded from a nozzle.

Regarding the information from Table 1, the researchers listed what they believe are the most important milestones, starting with research into developing feedstock for food 3D printing in 2009. The next year, after “promising results of tailor-fitted food textures,” researchers investigated the effect of additives on shape fidelity of 3D printed structures before and after cooking and deep frying.

“3D food printing has been employed to design appropriate insect products as a new source of proteins to overcome the disgust of consumers by consuming whole insects. An example of 3D printing technology applied to edible insects is represented by Soares and Forkes [82] in 2014, who printed the flour made out of edible dried insects in combination with fondant to produce icing for top cakes’ decoration,” the team wrote.

“Further work was carried out by Severini et al. [83] to obtain snacks from insect-enriched wheat flour dough as a new source of proteins.”

Researchers used inkjet printing in 2015 for microencapsulation processes – they developed a printhead with 500 nozzles that can fabricate monodisperse droplets that, once dry, turn into highly monodisperse powders. This allowed them to print alginate drops through a calcium chloride solution to make calcium alginate gel particles.

“In 2018, Vancauwenberghe et al. [86] designed a co-axial extrusion printhead to deposit a pectin-based ink and Ca2+ cross-linking solution in the inner and outer flows, respectively. This design facilitates an accurate control over the textural properties and gelation of the printing object as well as eliminates the pre-treatment or post-treatment step,” the researchers wrote.

That same year, another team compared the mechanical properties and textures of melted, untreated, 3D printed cheese samples, and determined that fat globules disrupt during printing, but partially coalesce as the print solidifies. Also in 2018, researchers compared the effects of freeze-drying and oven-drying on shape fidelity of 3D printed samples made from combined material sets of “cold swelling starch, milk powder, rye bran, oat, and faba bean protein concentrates and cellulose nanofiber.”

“Structural properties of the 3D object by varying infill structure has been investigated mostly in polymer and bio-printing,” they explained in reference to research about mashed potatoes.

“The textural and structural quality of mashed potatoes was investigated [96] by changing infill percentages (10%, 40%, 70%, and 100%) with different infill patterns (rectilinear, honeycomb, and Hilbert curve) and variation in shell perimeters (3, 5, and 7 shells).”

(Image: Fast Company)

Lest we forget about dessert, researchers in 2019 presented “semi-trained panelists” with three samples of chocolate that had been 3D printed in a honeycomb pattern with 25%, 50%, and 100% infill percentages, to see if printed objects with 100% infill have a lower breaking resistance than those fabricated with casting technology.

“From the works collected, it is clear that, even though studies have been steadily carried out over the last ten years, there have been few sequential linked developments of complexity and understanding of the chosen formulations. From this, an important factor in future uptake and advancement would be to focus on further developing these materials for more bespoke products and more detailed understanding,” the researchers note.

Finishing up with the future of 3D printing in the food industry, the team notes that while consumer acceptance is still a challenge, global food companies are using the technology, creating food 3D printers, and investing in the research.

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REVIEW: Zortax Inkspire sets high standard with photopolymerization market debut

Well-established as a manufacturer of desktop FFF 3D printers, Polish company Zortrax made its vat polymerization debut in September 2018 with the compact Inkspire system. Created for low-medium scale production, the Inkspire is marketed as an allrounder for use by engineering, jewelry, dental and design professionals. On its market entry, it also reported the ability […]

Florida Atlantic University Researcher Reviews Different Esophageal Stents, Including the 3D Printed Variety

Ranking sixth among all types of cancer in mortality, esophageal cancer kills about 16,000 people in the US annually, with about 500,000 new cases diagnosed around the world last year (according to the American Cancer Society). More than half of these patients are unfortunately diagnosed when the cancer is advanced enough that a tumor blocks the esophagus, which is typically when doctors insert a palliative, self-expanding esophageal stent to allow them to eat and drink. According to a paper, titled “A Review of Self-Expanding Esophageal Stents for the Palliation Therapy of Inoperable Esophageal Malignancies,” that was published by Florida Atlantic University researcher Dr. Yunqing Kang, researchers have been looking into other therapeutic applications for these stents.

The abstract reads, “Esophageal stents have evolved in stages over the years. Current clinically used stents commonly include stainless steel or nitinol self-expandable metallic stent (SEMS) and self-expandable plastic stent (SEPS). There are many choices of different types of stents and sizes, with fierce competition among manufacturers. However, current stent technology, whether uncovered, partially covered, fully covered SEMS or SEPS, has their own advantages to solve the dysphagia, stricture, and fistula problems, but they also cause some clinical complications. The ideal stent remains elusive. New 3D printing technique may bring new promising potential to manufacturing personalized esophageal stents. Drug-eluting stents could be the new avenue to do more than just pry open a stricture or cover a defect in the esophageal lumen, a possibility of proving local anticancer therapy simultaneously. Additionally, the lack of esophageal cancer animal models also hinders the progress of stent development. This paper reviews these topics for a comprehensive understanding of this field. In a conclusion, the ultimate goal of the future esophageal stent would have multifunction to treat the underlying conditions and restore esophageal function to near normal.”

Dr. Kang was actually the recipient of a $141,743 grant three years ago to develop a biodegradable, 3D printed polymer stent that could avoid the complications of metal stents, while at the same time serve as a drug delivery system. He has obviously continued his work, and in this study, he reviewed the applications of a variety of stents, including self-expanding, biodegradable, 3D printed, and drug-eluting.

Self-expanding metal stents, or SEMS, are the most widely used kind for malignant esophageal cancer, and come in covered, uncovered, and partially uncovered. However, use of SEMS has led to complications like recurrence of tissue growth, bleeding, fistulas, and stent migration. Because they don’t have the painful, rigid metal ends of SEMS, self-expanding plastic stents (SEPS) don’t cause these issues, and can also be easily removed. In addition, they can improve quality of life and dysphagia, and reduce how many dilatation sessions patients with benign structures require. But, while studies show that SEPS have a much higher rate of migration than SEMS, they are often used to treat perforations, fistulas, and esophageal leaks.

“Although SEPS causes high rate of migration, it appears to be safer than metallic stent as the plastic material may not cause significant tissue trauma,” Dr. Kang wrote.

Biodegradable (BD) stents were developed to reduce the number of complications from migration and growth of hyperplastic and tumor growth tissue, as well as to avoid removal.

“Two types of biodegradable polymer stents are available currently,” Dr. Kang wrote. “One is the ELLA-BD stent (ELLA-CS, Hradec Kralove, Czech Republic), which is composed of polydioxanone, a surgical suture material (Figure 2(b)) [35], and the other one is the poly-L-lactic acid (PLLA)-BDstent (Marui Textile Machinery, Osaka, Japan), which consists of knitted PLLA monofilaments [23].”

Biodegradable stents don’t need to be removed once they’re implanted, which means less time on the operating table for patients, and less chance of recurrent dysphagia. But, studies show they’re still likely to migrate, which causes the patient pain.

Dr. Yunqing Kang. [Image: Florida Atlantic University]

“From these results, it can be seen that although biodegradable stents may provide a valuable alternative to SEPS and SEMS, and also may eliminate the need for repeat esophageal dilations, biodegradable stents still presented some complications of migration and tissue regrowth. Also, biodegradation may lead to the collapse of stents after placement due to the collapsed degradation of the stent, quickly losing the mechanical strength,” Dr. Kang explained. “From these studies, it can be seen that the degradation properties of a BD stent determine its mechanical integrity. Studies showed that both ELLA-BD stent and PLLA-BD stents, the two currently available BD stents, can be degraded by hydrolysis, which is accelerated at low ambient pH. The stents began to degrade after 4 to 5 weeks and dissolved during a period of 2 to 3 months.”

Dr. Kang concluded that longer term studies are still needed to investigate “the relative efficacy or safety of esophageal biodegradable stents.”

“Therefore, the question of which type of stent should be recommended for the effective treatment of complex and refractory benign strictures, also malignant tumor remains unclear.”

3D printing is also used to create a variety of stents, such as airway stents, vascular stents, and biodegradable stents as well. The technology offers advantages over conventional fabrication of polymer stents, and is our best shot for personalization.

Photographs show the different types of 3D printed stents with different structures and material ratios (a). The stent was compressed and then recovered to the original shape (b).

“In our study, we used a 3D printing technology to produce a flexible polymer esophageal stent (Figure 3) [49]. We found that our 3D printing technique can print an esophageal stent with different size and shape,” Dr. Kang explained. “This is the first study using 3D printing technique to produce a polymer esophageal stent. Although the function of the 3D-printed flexible polymer stent has not been proved in vivo, the in vitro study showed that the 3D-printed esophageal stent has promising potential to treat malignant esophageal diseases. It can self-expand, and 3D printing technique can design and print different sizes and shapes of the stent easily.”

Again, the researcher noted that more study was required.

Dr. Kang also looked at drug-eluting stents (DESs), which are good for vascular applications but not clinically available yet to help treat esophageal cancer. Studies continues on this, and researchers have tried loading anticancer drugs, like 5-fluorouracil and paclitaxel, and whether sustained release of a stent with a bilayer film structure was possible.

“This kind of localized sustained delivery system in combination with the stent appeared to be a promising strategy to treat malignant esophagus cancer,” Dr. Kang wrote.

Esophageal cancer cells [Image: Reuters]

Finally, many types of models, like 3D cell spheroid models and animal xenograft/orthotopic ones, are used to evaluate the functionality and efficacy of a new drug delivery or treatment in cancer studies. But it’s not as easy for esophageal cancers with strictures, or benign esophageal diseases, due to the diameter and length of most FDA-approved stents not being applicable in these models. Dr. Kang stated that we need larger-sized animal models, like pigs or dogs, to study esophageal cancer and stents.

“The challenge is not only because of the complex surgery on a large animal, but also the potential difficulty of inoculating tumor cells or tissue in the orthotopic esophagus for tumor formation,” Dr. Kang explained. “In the future, new animal models or alternative animal modelling technologies still need to be developed and established for esophageal cancer stenting.”

I don’t enjoy thinking about testing medical theories out on animals, but I admit I see the point of needing larger animals for a necessary evil such as this.

Currently, popular palliation therapies for patients with inoperable esophageal malignancies suffering from dysphagia who use esophageal stents includes SEMS, SEPS, and biodegradable stents. But, as Dr. Kang’s research shows, novel stents that can get around some of the existing complications are desperately needed.

“In addition to improving the functionality of the drug-loaded stent with markedly reduced adverse effects, new ideal stents will allow to be tailored to individual needs at much lower cost,” Dr. Kang concluded. “Additionally, there is an unmet need to develop a large animal esophageal cancer model in vivo and establish a functional esophageal cancer model in vitro to test stents and study esophageal cancers.”

Discuss this research, and other 3D printing topics, at 3DPrintBoard.com or share your thoughts below. 

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With a promise to, “turn your desktop into a workshop” Snapmaker combines a 3D printer, laser engraver and CNC carver. A hugely successful Kickstarter campaign raised $2.2 million, and now the Snapmaker 3-in-1 3D printer is available for a wider audience. 3D Printing Industry tested the Snapmaker 3-in-1 3D printer against the claims made for […]